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Effects of Prescribing 1,000 versus 1,500 Kilocalories per Day in the Behavioral Treatment of Obesity: A Randomized Trial

January 17, 20182 min read

HHS Public Access Author manuscript Obesity (Silver Spring). Author manuscript; available in PMC 2018 January 17.

Published in final edited form as: Obesity (Silver Spring). 2013 December ; 21(12): 2481–2487. doi:10.1002/oby.20439.

Effects of Prescribing 1,000 versus 1,500 Kilocalories per Day in the Behavioral Treatment of Obesity: A Randomized Trial

Lisa M. Nackers1, Kathryn R. Middleton1, Pamela J. Dubyak1, Michael J. Daniels2, Stephen D. Anton3, and Michael G. Perri1

1Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida, USA

2Department of Statistics, University of Florida, Gainesville, Florida, USA

3Department of Aging and Geriatric Research, University of Florida, Gainesville, Florida, USA

Abstract

Objective—Controversy exists regarding the optimal energy prescription to promote successful long-term behavioral management of obesity. Prescribing intake of 1,000 (vs. 1,500) kcal/day may produce larger initial weight reduction, but long-term advantage remains unclear. The effects of prescribing 1,000 versus 1,500 kcal/day on 6- and 12-month weight changes within behavioral treatment of obesity were examined. Design and

Methods—Participants were 125 obese women (mean ± SD; BMI ¼ 37.84 ± 3.94 kg/m2 ) randomly assigned goals of 1,000 or 1,500 kcal/day.

Results—From months 0 to 6, participants prescribed 1,000 kcal/day lost more weight than those prescribed 1,500 kcal/day (mean ± SE = −10.03 ± 0.92g vs. −6.23 ± 0.94 kg, P = 0.045); however, from months 7 through 12, only the 1,000 kcal/day condition experienced a significant weight regain (1.51 ± 0.77 kg, P ¼ 0.025). Baseline caloric consumption moderated the effect of treatment on regain; participants with baseline intakes ≥2,000 kcal/day who were assigned 1,000 kcal/day were significantly more susceptible to weight regain than those assigned 1,500 kcal/day (P = 0.049). At month 12, a significantly greater percentage of 1,000 kcal/day participants achieved weight reductions of 5% or more than those prescribed 1,500 kcal/day.

Conclusion—Encouraging obese individuals in behavioral treatment to adhere to a 1,000 kcal/day intake may increase their likelihood of achieving clinically meaningful weight losses.

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Stephen Anton, PhD

Stephen Anton, PhD

Dr. Anton’s specific research interests are in the role that lifestyle factors have in influencing obesity, cardiovascular disease, and metabolic disease conditions. He completed his doctoral degree in Clinical and Health Psychology at the University of Florida (UF), receiving training in health promotion and the delivery of lifestyle interventions designed to modify eating and exercise behaviors. Following completion of his post-doctoral fellowship at the Pennington Biomedical Research Center in June 2007, he accepted a joint Assistant Professor position within the Department of Aging and Geriatric Research and Department of Clinical and Health Psychology at the University of Florida. Since joining the University of Florida, he has successfully obtained and conducted multiple grants examining the effects that lifestyle-based interventions have on biological and functional outcomes relevant to obesity, cardiovascular disease, and metabolic disease conditions related to aging. With over 150 scientific articles and book chapters, his research has been recognized both nationally as well as internationally.

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